infertility nejm honc pathophysiology clinical melanoma peds im genetics pediatrics syndrome 21ohd

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Prader-Willi Syndrome: Pathogenesis and clinical findings
• Maternal uniparental disomy: inheriting 2 copies of maternal chromosome

Prader-Willi Syndrome ... Pathogenesis and clinical ... delayed puberty -> Infertility ... #genetics #pathophysiology ... #peds #pediatrics

21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase

Pathogenesis and Clinical ... Hirsutism & acne • Infertility ... #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics

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