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differential myopathy neurology autoimmune comparison dermatology idiopathic iims management myelitis rash transverse vasculitis
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Inflammatory Myopathies ... Anti-MDA5, anti-Mi ... Associated Features: Weakness ... #rheumatology # ... table
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
RASH + MUSCLE WEAKNESS ... • Overlap Myositis ... Inclusion body myositis ... Severe proximal weakness ... #diagnosis #rheumatology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Diagnosis Framework ... • Metabolic myopathies ... EMG) studies • MRI ... certain drug-induced myopathies ... #Differential #Diagnosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Overview Focal inflammatory ... Weakness: - Weakness ... Diagnosis: • ... out compressive myelopathies ... Post Vaccine • Inflammatory
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Framework Inflammatory ... Myopathies: Commonly ... , drug-induced myopathies ... RP-ILD), dermato-rheumatologic ... #Myopathy #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Myalgia and muscle weakness ... oligoclonal bands • MRI ... syndrome: Ocular inflammatory ... #Rheumatology
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