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diagnosis causes differential symptoms genetics pediatrics 21hydroxylasedeficiency 21ohd adrenal bulimianervosa complications cushings excess gh growthhormone hirsutism hypercortisolism hyperfunction hypertension indications
Cushing Syndrome Testing Algorithm INDICATIONS FOR TESTING: • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension) Testing:
Cushing Syndrome ... Testing Algorithm ... syndrome (central ... Adrenocorticotropic Hormone ... #algorithm #endocrinology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Signs/Symptoms ... delayed puberty -> Infertility ... #genetics #pathophysiology ... #peds #pediatrics
Hirsutism & Virilization - Differential Diagnosis Algorithm ADRENAL EXCESS Ovarian • Polycystic Ovarian Syndrome • Hyperthecosis • Tumor Adrenal
Differential Diagnosis Algorithm ... Hyperplasia • Cushing's ... Low Serum Hormone ... Differential #Diagnosis #Algorithm ... #endocrinology
Weight Gain / Obesity - Differential Diagnosis Algorithm Decreased Expenditure: • Sedentary Lifestyle • Smoking Cessation
Differential Diagnosis Algorithm ... Polycystic Ovarian Syndrome ... Hypothyroid • Cushing's ... Iatrogenic: • Drugs/Hormones ... #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... Hirsutism & acne • Infertility ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Cushing's Syndrome ... melanocyte stimulating hormone ... #Syndrome #Hypercortisolism ... #Diagnosis #signs ... #symptoms #endocrinology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
hypertension and signs ... renal bruit or signs ... of hormonal excess ... Vasculitis • Endocrinologic ... Hypercalcemia, Cushing's
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
• Boerhaave syndrome ... of nutrients, hormonal ... VitD) and lowered hormone ... Complications #pathophysiology ... #diagnosis #signs
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