7 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Tubular Defects Fanconi ... loop of Henle Gitelman ... #Fanconi #Bartter ... Nephron #Defects #Pathophysiology ... #Nephrology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... Hirsutism & acne • Infertility ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
intoxication Cause ... - Bartter - Gitelman ... SIGNS: • Muscle ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... heart failure, neurologic ... renal bruit or signs ... Vasculitis • Endocrinologic ... Neurologic disorders
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Locked-in syndrome ... • Mutism Pathophysiology ... • Examine for signs ... Casey Albin MD @ ... #PhysicalExam #neurology
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
• Boerhaave syndrome ... > Amenorrhea & Infertility ... hormone levels cause ... Complications #pathophysiology ... #diagnosis #signs