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diagnosis galactomannan betadglucan infections infectiousdiseases management aspgm bdg bdglucan candida chest comparison ddx empyema en falsepositives fungi granuloma ia id
Fungal biomarkers Beta-d-glucan Aspergillus galactomannan By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com] #ID #Infectious Diseases #Infections #Differential #Ddx
Fungal biomarkers ... Beta-d-glucan Aspergillus ... #Infections #Differential ... #Fungi #BDG #BDGlucan ... galactomannan #Aspergillus
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... component of many fungi ... cut-offs defined in clinical ... GM does not differentiate ... #Biomarkers #BetaDGlucan
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
HIV/AIDS, CGD) Clinical ... in SOT pts) • BAL ... this morphology Treatment ... Diagnosis #Management #treatment ... #fungal #infectiousdiseases
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
component of many fungi ... cut-offs defined in clinical ... >90% (In most clinical ... does not differentiate ... closely related fungi
Empyema Necessitans (EN) on Chest Wall Physical Examination Pulmonary teaching case: you are called to the bedside
most common) - Fungus ... , Blastomyces, Aspergillus ... Fusobacterium Treatment ... covering the right bug ... #PhysicalExam #clinical
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 Majocchi’s Granuloma due to Trichophyton rubrum This is GMS stain and culture of a skin biopsy
Treatment: Itraconazole ... Non-dermatophytes: Aspergillus ... Majocchi granuloma Treatment ... recommended Mayo Clinic ... #photo #microscopy
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
body • Bird and bat ... has five major clinical ... Diagnosis: • Direct fungal ... stain of clinical ... ASPERGILLOSIS • Aspergillus
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