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diagnosis aspergillus galactomannan betadglucan management syndrome antibiotic aspgm bdglucan candida chest comparison ddx empyema en failure falsepositives fungi ia id
Fungal biomarkers Beta-d-glucan Aspergillus galactomannan By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com] #ID #Infectious Diseases #Infections #Differential #Ddx
Fungal biomarkers ... #Infections #Differential ... Ddx #Diagnosis #Fungal ... #Fungi #BDG #BDGlucan
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... Specificity: - Serum BDG ... cut-offs defined in clinical ... should not increase BDG ... GM does not differentiate
Purple Urine Bag Syndrome Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine Tryptophan → Indoxyl
Purple Urine Bag ... Purple #Urine #Bag ... pathophysiology #clinical ... #photo #differential
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Antibiotic Failure - Differential ... , VTE • Wrong Bug ... bacteria: Viral, Fungal ... Immunocompromise Treatment ... • Secondary to Treatment
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
HIV/AIDS, CGD) Clinical ... Penicillium • BDG ... this morphology Treatment ... Diagnosis #Management #treatment ... #fungal #infectiousdiseases
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
component of many fungi ... cut-offs defined in clinical ... synthetic and do not TBDG ... >90% (In most clinical ... does not differentiate
Empyema Necessitans (EN) on Chest Wall Physical Examination Pulmonary teaching case: you are called to the bedside
most common) - Fungus ... Fusobacterium Treatment ... covering the right bug ... #PhysicalExam #clinical
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 Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
noncompliance • Clinical ... initiation Clinical ... Calmette-Guérin (BCG ... Leishmaniasis Differential ... Inflammatory #Syndrome #Differential
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