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diagnosis hematology treatment arthritis differential hemophagocytic joint lymphohistiocytosis pain product reactions workup approach calcium classification cppd deposition fungal hemophilia hodgkins
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... presents as an acute ... • Infection should ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... • Autoimmune diseases ... Adult-onset Still disease ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... with established disease ... severity Treatment - Acute ... #treatment #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Transfusion Related Acute ... donors (due to anti-HLA ... Transfusions #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... Transfusion Related Acute ... donors (due to anti-HLA ... Transfusion #diagnosis #management ... #hematology #reactions
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
the time course (acute ... axial (spine, shoulders ... - Autoimmune Rheumatologic ... Differential #Diagnosis #MSK ... #rheumatology #
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full Blood ... marrow biopsy - if blood ... number of sites of disease ... classification #hematology ... #oncology #management
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
), RA, crystal disease ... tumor • Non-bloody ... Like in this case ... #Joint #Pain #MSK ... #rheumatology #
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Diagnosis and Management ... orbital pain, (Sub)acute ... ON: should be considered ... other auto-immune diseases ... #treatment #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... antibodies, which are ... ANAs RF test should ... Screening Tests for Acute ... : • Complete blood
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