13 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... presents as an acute ... the main goal of ... management #treatment #hematology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... -> Trauma, disc ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
dihydrate • Basic calcium ... Arthritis: • Acute ... Previous joint trauma ... #MSK #rheumatology ... #differential #diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... Noninflammatory • Trauma ... #Differential #Diagnosis ... #MSK #rheumatology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... fibrosis. 4) Calcium ... anterior/posterior MSK ... : ACUTE, fever, ... #Management #Signs
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... - Diagnostic Framework ... Like in this case ... #Joint #Pain #MSK ... #rheumatology #
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Sensitivity to pain ... Multiple Sclerosis Diagnosis ... Oligoclonal bands are ... symptoms) • Acute
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
after surgery/trauma ... precipitates with calcium ... onset of swelling, pain ... • Metabolic syndrome ... Gout #Comparison #rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
sex • Metabolic syndrome ... swelling, significant pain ... double contour sign ... +Radiographic signs ... management #treatment #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
after surgery/trauma ... onset of swelling, pain ... Crowned Dens Syndrome ... neck pain, fever ... Deposition #Disease #Rheumatology