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hematology differential abnormal anemia atlas beaus causes chronic clinical diseases extravascular fingernails hemolysis hemolytic hemophagocytic hlh intravascular leukemia lymphocytic lymphohistiocytosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
large numbers and are ... Physical Exam/Signs ... Diagnosis: • ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... • Mechanical Trauma ... ) - HELLP syndrome ... ) (e.g. lupus, CLL ... #hematology #anemia
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... Low or absent NK cell ... insulting agent are ... management #treatment #hematology
Nail Pathologies - Findings in or Near Nails Paronychia A superficial infection of the proximal and lateral
The nail folds are ... Commonly affects all ... seen in Reiter's syndrome ... Abnormal #Pathology #Diagnosis ... #Clinical #Signs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... diseases to exclude are ... purpura: Strong sign ... CRP GCA (Giant Cell ... #Rheumatology
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