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hemophagocytic oncology activation behcet chronic classification cll fungal hodgkins leukemia lymphocytic lymphoma macrophage mas polychondritis relapsing signs summary workup
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... accumulation of clinical ... toxoplasmosis,...), Mycosis ... #diagnosis #management ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... : HLH signs and ... #diagnosis #management ... #treatment #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
(HLH) that develops ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
(Clinical Dx). ... Arthritis, AS Treatment ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... weeks without infection ... Physical Exam/Signs ... workup #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma - Clinical ... ingestion • B symptoms ... classification #hematology ... #oncology #management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Mycoses HISTOPLASMOSIS ... • Rheumatologic ... has five major clinical ... #InfectiousDiseases ... #Management #Infections
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... • Infections ... affected tissue Treatment ... Polychondritis #rheumatology ... #diagnosis #management
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