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rheumatology chronic differential symptoms abnormal aclf activation acute algorithm causes cirrhosis enzymes gastroenterology hemophagocytic hlh hypertension leukemia lfts lymphocytic lymphohistiocytosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Clinical Guidelines ... months without treatment ... disease, liver ... #Hepatology #gastroenterology ... #management #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... : HLH signs and ... #management #treatment ... #hematology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... significant portal HTN Signs ... obstruction) • Lack of signs ... including R heart failure ... #causes #hepatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... cells can indicate disease ... • Bone marrow failure ... workup #oncology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
of multiorgan failure ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
symptoms/signs ... box indicates all ... presence of metabolic syndrome ... disease; T2DM, ... Abnormal #Algorithm #Hepatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... syndrome (Clinical ... Arthritis, AS Treatment ... #Syndrome #diagnosis ... #management #signs
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
dysregulation: activated macrophages ... possibly renal failure ... Clinical Features ... heart (2-5%), liver ... #Management #Signs
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Males • Affects all ... arrhythmia • Heart failure ... Sarcoidosis • Behcet ... affected tissue Treatment ... #diagnosis #management
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