20 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... eosinophilia (common ... organ-specific signs ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
: • Most common ... Orange or Hep C Clinical ... Physical Exam/Signs ... cells can indicate disease ... workup #oncology #hematology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... #rheumatology # ... dermatology #diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoid malignancy (CLL ... Viral Infection Clinical ... symptoms - most common ... malignancies -> CLL ... hemolytic #anemia #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
leukemia in adults • Disorder ... immunophenotype Clinical ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... to impaired B-cell ... to 8 years Clinical ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... : HLH signs and ... symptoms can mimic common ... #hematology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
acute ischemic disorder ... Clinical manifestations ... Doppler US : halo sign ... GiantCellArteritis #GCA #Rheumatology ... #Algorithm
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... #diagnosis #management ... #rheumatology # ... dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... , dermatomyositis ... common • Antihistone ... #Rheumatology