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management arthritis differential workup pain approach chronic classification cll fungal gout hematology infections infectiousdiseases leukemia lymphocytic monoarthritis monoarticular mycoses neuritis
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
of hands/feet, knees ... , shoulders Signs ... & Symptoms: • ... exam and imaging Treatment ... ideally limit for acute
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
elbows/wrists and knees ... and Symptoms: ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... present both at rest ... Arthritis: • Acute ... #Pain #MSK #rheumatology ... #differential #diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... #Differential #Diagnosis ... #MSK #rheumatology
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Optic Neuritis - Diagnosis ... caucasian • Symptoms ... orbital pain, (Sub)acute ... Unilateral • Signs ... #rheumatology #
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
presents with acute ... symptoms • Rheumatologic ... to 12 weeks for acute ... muscle aches, joint ... : • Acute or chronic
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
deposition in joints ... attacks • Other joints ... forefoot, ankles, knees ... double contour sign ... #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... with no early symptoms ... Physical Exam/Signs ... microglobulin Treatment ... ’s lymphoma or acute
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... Presentation - Systemic Symptoms ... purpura: strong sign ... retinopathy Lab Tests ... #rheumatology #
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