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diagnosis management differential pathophysiology clinical pharmacology algorithm causes dermatology hematology allergy photo treatment classification comparison syndrome table signs cardiology medications
Immune Reactions and Immunosuppressant Drugs Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2 Muromonab-CD3 - Monoclonal antibody Calcineurin
Immune Reactions ... Inhibition of cytokine ... Inhibition of cytokine
KSHV Inflammatory Cytokine Syndrome (KICS) By Dr. Sara Dong @swinndong via #IDFellowCase #ID #Infectious Diseases
KSHV Inflammatory ... Cytokine Syndrome ... Ddx #Diagnosis #KSHV
Kaposi Sarcoma Herpes Virus (KSHV) By Dr. Sara Dong @swinndong via #IDFellowCase #ID #Infectious Diseases #Infections #Differential
Herpes Virus (KSHV ... Ddx #Diagnosis #KSHV
Hypothermia in Sepsis - Pathophysiology • 20% of septic pts → HYPOTHERMIA • Increased mortality 62%
proinflammatory cytokines ... anti-inflammatory cytokine
Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
eosinophilopoietic cytokines ... causes: - Drug reaction ... infection - Allergic reaction
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
hypersensitivity reactions ... Acute transfusion reaction ... release inflammatory cytokines ... hypersensitivity #reactions
KSHV Inflammatory Cytokine Syndrome (KICS) Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
KSHV Inflammatory ... Cytokine Syndrome ... 3) Evidence of KSHV ... activity - Elevated KSHV ... #Inflammatory #Cytokine
Estimated Incidence of Transfusion Reactions Graphical Depiction of transfusion reactions ordered from most highest to lowest incidence. #Diagnosis
of Transfusion Reactions ... of transfusion reactions ... Transfusion #Consent #Reactions
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Penicillin-induced drug reaction ... Dermatitis (ie. reaction ... Allergy #Allergic #Reactions
Anaphylaxis: Pathogenesis Anaphylaxis is a Type 1 hypersensitivity reaction While the primary mechanism of anaphylaxis is mast cell
hypersensitivity reaction ... mediators (e.g. cytokines
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