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diagnosis management differential hematology oncology syndrome behcet clinical fungal infections infectiousdiseases leukemia monoclonal mycoses myorhythmia oculomasticatory ophthalmology paraproteinemias physicalexam signs
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... skin injury) • Neurologic ... Leukemia, Lymphoma Ocular ... • Nonsurgical abdominal ... signs #symptoms #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
affects the skin, neurologic ... multiplex • GI tract: Abdominal ... cognitive impairment, neurologic ... gut involvement, abdominal ... Differential #Diagnosis #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... Sjogrens #Syndrome #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... involvement • 30%: CNS ... , weight loss, abdominal ... leukostasis syndrome: CNS ... #Leukemia #Hematology
Oculomasticatory Myorhythmia Pendular vergence oscillations of the eyes + concurrent contractions of the masticatory muscles. It's
for Whipple's disease ... with CNS involvement ... Whipples #clinical #video ... #neurology #ocular
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 Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... Scleromyxedema (CNS ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... Pulmonary 3) Abdominal ... especially the CNS ... MC: CNS CSF: • ... osteoarticular, pulmonary, ocular
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