28 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... #PraderWilli #Syndrome ... #peds #pediatrics
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... rasburicase Tumor Lysis Syndrome ... #Tumor #Lysis #Syndrome ... TLS #diagnosis #management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... - Compartment syndrome ... Neuroleptic malignant syndrome ... Dermatomyositis Clinical ... or compartment syndrome
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Refeeding Syndrome ... may cause severe clinical ... Epilepsy • Fanconi syndrome ... • Nephrotic syndrome ... #Refeeding #Syndrome
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... Risk factor for Late ... mutations - Down syndrome ... AlzheimersDisease #Dementia #pathophysiology ... diagnosis #signs #symptoms
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Pathogenesis and clinical ... share the same pathophysiology ... Carpal Tunnel Syndrome ... diagnosis #signs #symptoms ... endocrinology #pathophysiology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI - Pathophysiology ... Iinitial rate: 1
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Rhabdomyolysis • Difficulty ... Guillain-Barré syndrome ... antisynthetase syndrome ... Lambert-Eaton myasthenic syndrome ... myopathy #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Weakness: mild difficulty ... cardiomyopathy, Horner syndrome ... Miller Fisher Syndrome ... Guillain #Barre #Syndrome
Rare Causes of Abdominal Pain
 • Hereditary Angioneurotic Edema - Recurrent visceral that may by swelling
arcuate ligament syndrome ... mesenteric artery syndrome ... Ehlers-Danlos Syndrome ... incisional hernias: clinical ... Abdominal #Pain #differential