21 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... Risk factor for Late ... chromosome 21) Signs ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
Wellens' Sign: LAD-T Wave Inversion 
Life threatening T wave inversions in precordial leads. Often V2-V3 
Specific
Wellens' Sign: LAD-T ... Specific for critical ... High rate in <1 ... anterior wall MI ... Electrocardiogram #Diagnosis #Cardiology
Freiberg Infraction - MSK Radiology
Imaging Findings:
 • Sclerosis of the 2nd MT head with flattening of
Infraction - MSK Radiology ... for secondary signs ... Differential diagnosis ... Infraction #foot #clinical ... #mri #clinical
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
mass and NO prior signs ... or clinical history ... surgeon had a clinical ... Differential diagnosis ... #clinical #Radiology
Pulmonary Embolism on POCUS Echocardiogram

Mid 30's female with chest pain/dyspnea.  Triage EKG (no prior).
Sister had MI in ... Differential/diagnosis ... RV, McConnell's sign ... Echocardiogram #A4c #clinical ... #cardiology #McConnells
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... Signs/Symptoms/Complications ... , vomiting • Late ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds #pediatrics
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
workup 1) Clinical ... MRI, iADL scale, ... (parkinsonian signs ... MNCD #Dementia #Differential ... Workup #Diagnosis #Geriatrics
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... lateral sclerosis Pathophysiology ... features developing later ... MRI: Brain, cervical ... conditions listed in differential
Cannon A waves during AVNRT on Physical Exam
In AVNRT, the atria and ventricles contract nearly simultaneously
Cannon A per minute=rate ... excludes other differentials ... that’s called “clinical ... PhysicalExam #JVP #Cardiology ... #Neck #Frog #Sign
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... Collapse: • Pathophysiology ... → Syncope • Signs ... Decreased pulse rate ... - Athlete - difficulty