14 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... proliferation rate ... #TLS #diagnosis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... • Jaundice (later ... bile ducts Differential ... #workup #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
clinical symptoms/signs ... presence of metabolic syndrome ... #Algorithm #Hepatology ... Liver #Enzymes #Differential ... #Diagnosis
Abnormalities in Rate and Rhythm of Breathing 
Normal 
The respiratory rate is about 14—20 per min
Abnormalities in Rate ... punctuated by frequent sighs ... hyperventilation syndrome—a ... Occasional sighs ... #Diagnosis #PhysicalExam
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... initiation • Differential ... 500 mg QD until normal ... #management #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... synthesis rises later ... function may be abnormal ... #hepatology
Signs and Symptoms Associated With Different Headache Etiologies
 • Nonfocal mental status changes - Meningitis, encephalitis,
Signs and Symptoms ... Hypertension with normal ... #headache #signs ... symptoms #clues #differential ... #diagnosis
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... Diagnosis: • ... • Mutism Pathophysiology ... • Examine for signs ... caseyalbin #PhysicalExam
Newborn Infant - Routine Examination

Birthweight, gestational age and birthweight percentile are noted.
General observation Of the baby's
fontanelle is also a late ... sign of meningitis ... If abnormal, this ... When the diagnosis ... Newborn #Infant #PhysicalExam
Aortoenteric Fistula - Diagnosis and Management Summary
Epidemiology:
• Uncommon but life-threatening
• Most common site of bowel connection
duodenum Clinical Signs ... • Should be on differential ... that precedes a later ... Pathophysiology: ... - CMC IM Residency