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The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Without treatment ... - Late Latent ... - Late latent patients ... Late (Tertiary) ... Syphilis - Late
Syphilis - CDC 2021 Treatment Guidelines
Recommended Regimen:
 • Primary, secondary, and early latent: adults (including pregnant
Treatment Guidelines ... people with HIV infection ... million units IM ... single dose • Late ... million units IM
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Manifestations and Treatment ... Albuminuria, nephrotic syndrome ... Syphilis: • Patient ... • Late latent ... • Late latent
IDSA Recommendations for Treating Treponema pallidum Infections (Syphilis) to Prevent Disease in HIV-AIDS
Early Stage (Primary, Secondary,
(Syphilis) to Prevent ... Disease in HIV-AIDS ... 1 dose (BII) Late-Latent ... 28 days (BIII) Late-Stage ... IDSA #Prevention #Treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... the underlying pathophysiology ... and cauda equina TREATMENT ... Hospital of Baltimore IM ... Guillain #Barre #Syndrome
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... of HIV/AIDS patients ... be present: • AIDS ... progression of cirrhosis ... #Inflammatory #Syndrome
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Itraconazole is the agent ... yeast • At risk: AIDS ... , neutropenia, cirrhosis ... Aspergillosis Pathophysiology ... shock • Mortality rate