25 results
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... states Pathophysiology ... onset of swelling, pain ... swelling, significant pain ... Gout #Comparison #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Diagnosis Framework ... constitutional symptoms ... at night Pain ... • Adult onset ... #Diagnosis #MSK
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
or nerve root Symptoms ... of Joint Disease ... categories of joint disease ... #MSK #rheumatology ... #differential #diagnosis
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
(CPPD) Pathophysiology ... onset of swelling, pain ... with acute neck pain ... #Rheumatology # ... diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Epidemiology: • Young adults ... meningitis), MCC CNS symptoms ... Nonsurgical abdominal pain ... management #signs #symptoms ... #rheumatology #
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... 33% of healthy adults ... context of other symptoms ... ANA #patterns #rheumatology ... #diagnosis #differential
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... the chest/trunk Symptoms ... usually in the late ... early evening • Arthritis ... #rheumatology #
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Epidemiology: young adults ... Alcohol-induced pain ... : Pain in involved ... Differential Diagnosis ... #differential #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... - Diagnostic Framework ... = Worry about late ... #Joint #Pain #MSK ... #rheumatology #
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Adult form: Less ... nephrocalcinosis • CPPD ... Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... mineralization Symptoms