9 results
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
and Aspergillus Galactomannan ... & Specificity: ... invasive fungal infection ... surfaces - Infections ... BAL GM does not differentiate
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
Testing Sensitivity ... Specificity and ... 96% • Higher specificity ... surfaces, Albumin, Infections ... in BAL does not differentiate
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... 100%, specificity ... effect/Edema • EBV ... 92% and specificity ... #differential #
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... virus • CMV • EBV ... CSF has a 99% sensitivity ... and specificity ... and specificity
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Pneumocystis pneumonia (late ... > 1.5) with a sensitivity ... and specificity ... • Toxins • Infection
Aortoenteric Fistula - Diagnosis and Management Summary
Epidemiology:
• Uncommon but life-threatening
• Most common site of bowel connection
• Should be on differential ... that precedes a later ... Pathophysiology: ... undergo EGD - Sensitivity ... - CMC IM Residency
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Liver Injury: • Infectious ... HBV, HCV, HEV, EBV ... Assists in liver specificity ... synthesis rises later
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Direct microbial infection ... Hyperreflexia develops later ... Brucellosis - Dengue, EBV ... management #neurology #differential
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Disseminated Infections ... antigen assay has a sensitivity ... and specificity ... Aspergillosis Pathophysiology ... shock • Mortality rate