10 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... 100%, specificity ... effect/Edema • EBV ... 92% and specificity ... #differential #
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... overlook severe infections ... #Bandemia #differential ... neutrophil #WBC #CBC #hematology ... #pathophysiology
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... virus • CMV • EBV ... CSF has a 99% sensitivity ... and specificity ... and specificity
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Pneumocystis pneumonia (late ... > 1.5) with a sensitivity ... and specificity ... • Toxins • Infection
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Liver Injury: • Infectious ... Assists in liver specificity ... synthesis rises later ... diagnosis #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... • Jaundice (later ... bile ducts Differential ... fungal, viral infections ... diagnosis #workup #hepatology
Aortoenteric Fistula - Diagnosis and Management Summary
Epidemiology:
• Uncommon but life-threatening
• Most common site of bowel connection
• Should be on differential ... that precedes a later ... Pathophysiology: ... undergo EGD - Sensitivity ... - CMC IM Residency
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Direct microbial infection ... Hyperreflexia develops later ... Brucellosis - Dengue, EBV ... management #neurology #differential
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Include: • Viral infections ... acute HIV, HBV, EBV ... heavy/light chain specificity ... Gap #ProteinGap #differential ... #diagnosis #hematology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Disseminated Infections ... antigen assay has a sensitivity ... and specificity ... Aspergillosis Pathophysiology ... shock • Mortality rate