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diagnosis fungal infectiousdiseases galactomannan infections laboratory management visualabstract accuracy aids aorta aortic arthritis biomarkers biostatistics calculations chestct cns comparison coronavirus
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Galactomannan Testing ... Sensitivity Specificity ... 96% • Higher specificity ... >90% (In most clinical ... blood products #BetaDGlucan
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
& Specificity: ... cut-offs defined in clinical ... & Specificity ... Frozen ice-pops (in setting ... Fungal #Biomarkers #BetaDGlucan
Ohle R et al. Clinical Examination for Acute Aortic Dissection: A Systematic Review and Meta-analysis. AEM
Clinical Examination ... Dissection #Aorta #Testing ... Signs #Accuracy #Sensitivity ... #Specificity #SGEM ... VisualAbstract #EBM
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
HIV/AIDS, CGD) Clinical ... Diagnosis and Testing ... Galactomannan sensitivity ... associated with low sensitivity ... and low specificity
COVID19 Testing - PCR vs CT - Sensitivity and Specificity Original Data via https://pubs.rsna.org/doi/full/10.1148/radiol.2020200642 Admission laboratory patterns in
COVID19 Testing ... - PCR vs CT - Sensitivity ... and Specificity ... Internet Book of Critical ... VisualAbstract #EBM
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
should be based on clinical ... 100%, specificity ... effect/Edema • EBV ... of serum CrAg testing ... comparable to CSF testing
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
sedimentation rate ... - CCP antibody testing ... has higher specificity ... test but lower sensitivity ... ANA and RF (if clinical
USMLE Epidemiology and Biostatistics Summary Meta-Analysis: pools data from several studies (greater power), limited by quality/bias of
individual studies Clinical ... diseases, describe clinical ... Sensitivity (rule ... Specificity (rule ... alters recall Late-look
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
antigen assay has a sensitivity ... and specificity ... Urinary antigen testing ... ASPERGILLOSIS • Aspergillus ... Aspergillosis Pathophysiology
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