13 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... #Localization #Nephron ... #Defects #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... delivery to distal nephron ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Metabolic Alkalosis - Differential ... Vomiting, NGT suction ... intake, Diuretics (late ... , Gitelman Syndrome ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Metabolic Alkalosis - Differential ... Vomiting, NGT suction ... intake, Diuretics (late ... , Gitelman Syndrome ... Diagnosis #Algorithm #Nephrology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Hypochloremia - Differential ... - Bartter - Gitelman ... glomerular filtration rate ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Vomiting • NG suction ... Hypomagnesemia • Barrter's/Gitelman's ... Licorice • Liddle's Syndrome ... MetabolicAlkalosis #NonGap #Nephrology ... #Differential #
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
blood pressure: Active ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... urine #Algorithm #nephrology ... #differential #
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
excess, Liddle syndrome ... Non-reabsorbable anion ... , Gitelman syndrome ... urine #potassium #differential ... algorithm #diagnosis #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Metabolic Alkalosis - Differential ... Vomiting, NGT suction ... intake, Diuretics (late ... , Gitelman Syndrome ... Diagnosis #Algorithm #Nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... cotransporter • Gitelman's ... ratio 0.5%) Differential ... #nephrology #management ... #pathophysiology