11 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... delivery to distal nephron ... → Hypokalemia Metabolic ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... Vomiting, NGT suction ... intake, Diuretics (late ... Bartter Syndrome, Gitelman ... #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Vomiting, NGT suction ... intake, Diuretics (late ... Bartter Syndrome, Gitelman ... #Algorithm #Nephrology
Metabolic and Respiratory Acidosis and Alkalosis - Diagnostic Algorithm

Anion gap - MUDPILES: 
 - Methanol (formic
Metabolic and Respiratory ... and Alkalosis - Diagnostic ... - Salicylates (late ... infusion #Diagnosis ... Recommended Text: Nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
blood pressure: Active ... Bartter syndrome, Gitelman ... tubular acidosis Anion ... urine #Algorithm #nephrology ... #differential #diagnosis
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Gap Metabolic Acidosis ... Generalized distal nephron ... aniongap #NonGap #Metabolic ... #differential #diagnosis ... #causes #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic ... - Differential Diagnosis ... Vomiting • NG suction ... Hypomagnesemia • Barrter's/Gitelman's ... MetabolicAlkalosis #NonGap #Nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Vomiting, NGT suction ... intake, Diuretics (late ... Bartter Syndrome, Gitelman ... #Algorithm #Nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
: Differential Diagnosis ... vomiting/ nasogastric suction ... furosemide-like lesion) • Gitelman ... #Differential #Diagnosis ... #Causes #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
hypomagnesemia • Metabolic ... Hypochloremic metabolic ... #Syndrome #diagnosis ... #nephrology #management ... #pathophysiology