54 results
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Adrenal Insufficiency ... Diagnosis Algorithm ... findings (see algorithm ... #Diagnosis #Algorithm ... #StimTest #Endocrinology
Adrenal Insufficiency Algorithm - Cosyntropin Stimulation Test
T-1m: Baseline cortisol drawn
T0: 250 µg cosyntropin given IV
T30m: Repeat
Adrenal Insufficiency ... Algorithm - Cosyntropin ... Stimulation Test ... #Insufficiency ... #endocrinology
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Adrenal Insufficiency ... Differential Diagnosis Algorithm ... Weakness, fatigue, nausea ... hormone (ACTH) stimulation ... #endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Test 1: Baseline AM Cortisol 
 - Beware of major normal value
 -
Adrenal Insufficiency ... Diagnosis Algorithm ... ) Test 2: ACTH Stimulation ... #Insufficiency ... #endocrinology
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm
Primary Adrenal Insufficiency:
 • Autoimmune primary adrenal insufficiency
 • Adrenoleukodystrophy,
Adrenal Insufficiency ... Diagnosis Workup Algorithm ... #Adrenal #Insufficiency ... Diagnosis #Workup #Algorithm ... #endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... Diagnosis Algorithm ... unclear (often the case ... #ACTH #Stimulation ... #Test #Endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Causes of Adrenal ... Insufficiency - ... Differential Diagnosis Algorithm ... #Insufficiency ... #Causes #endocrinology
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Insufficiency: ... • ACTH stimulation ... aldosterone - Low in cases ... • ACTH stimulation ... diagnosis #testing #endocrinology
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Primary vs Secondary Adrenal ... Insufficiency - ... stimulation, thus ... #Insufficiency ... Pathophysiology #endocrinology
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Insufficiency - ... Algorithm Step ... #Insufficiency ... #ACTH #Stimulation ... #Endocrinology