28 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... : Chronic infections ... Diagnosis #Algorithm #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
: • Recurrent infections ... megaloblastic anemia Treatment ... if neutropenic fever ... diagnosis #management #treatment ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
SLE) - Viral infections ... Kasabach-Merritt syndrome ... mountain spotted fever ... Differential #Diagnosis #hematology ... #rheumatology #
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... risk-stratification • Risks: infection ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
common route of infection ... Cardiopulmonary Syndrome ... • Prodrome: fever ... • Autopsy PCR Treatment ... #microbiology #
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
parvovirus B19 infection ... • Rheumatic fever ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
- Nonremitting fever ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... can mimic common infections ... following: • Fever ... : • Infection ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... /fevers • Thrombocytopenia ... Idiopathic • Infections ... aplastic anemia Treatment ... Anemia #oncology #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... Low calcium • Treatment ... - Hyperkalemia treatment ... diagnosis #management #hematology