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diagnosis hematology management oncology chronic cll hlh lymphocytic lymphohistiocytosis activation anemia aplastic cancer hemeonc macrophage mas summary syndrome workup
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
A subset of hemophagocytic ... syndromes Clinical ... is the main clinical ... Treatment: • Corticosteroids ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... accumulation of clinical ... Assessment • Clinical ... : fever +++, hepatosplenomegaly ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... : Overwhelming clinical ... following: • Fever ... • Bicytopenia Treatment ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... Orange or Hep C Clinical ... Lymphadenopathy • Fevers ... microglobulin Treatment ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... immunophenotype Clinical ... ) B symptoms → fevers ... #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... Presentation: • Fever ... recurrent infections/fevers ... virus (EBV) • Leukemia ... aplastic anemia Treatment
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... algorithm 2018. ... acute myeloid leukemia ... importance of clinical ... #algorithm #hematology
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