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diagnosis management hematology oncology differential hemophagocytic hlh infectiousdiseases leukemia lymphohistiocytosis tb tuberculosis activation bcx bloodculture bloodcx calcium cardiology chronic classification
Blood culture contaminants Grouped by gram negative vs gram positive vs other as well as never/maybe/probably Some additional
other as well as never ... febrilepodcast] #ID ... #Infectious Diseases ... #Infections #Microbiology ... #Differential #Ddx
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• DM DDX: ... TB: • Fever • ... Tuberculosis Treatment ... Initiating Treatment ... #ActiveTB #LatentTB
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• DM DDX: ... TB: • Fever • ... Tuberculosis Treatment ... Initiating Treatment ... #ActiveTB #LatentTB
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Periodic fever ... kidney failure DDX ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... following: • Fever ... absent NK cell activity ... : • Infection ... #hematology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
respiratory symptoms • Fever ... pulmonary symptoms • Rheumatologic ... nonspecific • DX ... • Cough, fever ... • Isolated fever
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... weeks without infection ... cells can indicate disease ... Scoring system: DDX ... microglobulin Treatment
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Tyrosine Kinase activity ... Headaches, bone pain, fever ... plaques) AML Dx ... Lymphadenopathy • HSM • Fevers
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Hypercoagulable (APLAS) Microbiology ... night sweats, fever ... Glomerulonephritis DDX ... hematuria, + RF Treatment ... Persistent bacteremia/fevers
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
include low-grade fevers ... with restricted active ... hypothyroidism, infection ... TREATMENT: • The ... Diagnosis #Management #Rheumatology
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