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disease stills syndrome activation adult adultonset common cvid fungal hypogammaglobulinemia immunodeficiency immunology infections infectiousdiseases macrophage mas mycoses onset sjogrens treatment
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
, difficult to diagnose ... malignant) to diagnose ... episode (30%) Systemic ... #rheumatology # ... diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE], AOSD ... thrombocytopenia • Liver ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Still's Disease Systemic ... /splenomegaly, liver ... Stills #disease #AOSD ... #diagnosis #rheumatology ... #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disease • Liver ... hemolytic anemia) • Systemic ... and M panel Management ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Central nervous system ... vasculitis: 10%-16% Liver ... Nephrogenic DI Hematologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
conidia → Yeast → travel ... pulmonary symptoms • Rheumatologic ... Mississippi and Ohio River ... the circulatory system ... #Management #Infections
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