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hemophagocytic lymphohistiocytosis product reactions rheumatology treatment activation classification differential empiric hodgkins lymphoma macrophage mas oncology returning summary syndrome transfusion transfusions
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... Diagnosis via genetic ... following: • Fever ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Auto-amplification loop Diagnosis ... • Clinical: fever ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... - Nonremitting fever ... Histopathologic criteria ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Fever in the Returning International Traveler Investigations after comprehensive physical examination including thorough skin examination: •
Malaria Smears, Blood ... Arbovirus Empiric Management ... the following criteria ... #empiric #management ... #workup #diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Workup: • Full Blood ... through Ann Arbor criteria ... classification #hematology ... #oncology #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
S/sx: Fever, flank ... donors (due to anti-HLA ... Sx include: fever ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... donors (due to anti-HLA ... Sx include: fever ... #Transfusion #diagnosis ... #management #hematology
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