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disease hematology hemophagocytic hlh lymphohistiocytosis macrophage mas onset stills summary syndrome treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... arthritis (sJIA) • Adult-onset ... erythematosus [SLE], AOSD ... #Syndrome #Diagnosis ... #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... Phagocytosis of blood ... diseases: SLE+++, Adult-onset ... #management #treatment ... #summary #rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... maculopapular skin ... Stills #disease #AOSD ... #diagnosis #rheumatology ... #management
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