10 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... should be based on clinical ... Inferomedial temporal lobes ... effect/Edema • EBV ... #differential #
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... - Mycoplasma, EBV ... , HIV, rubella legionella ... younger pts) Differential ... Disorders Such As
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Progression: • Upper lobe ... characteristic features Clinical ... and quantiferon-gold ... staining, NAA (PCR ... TB #Diagnosis #Management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... matter, spinal cord ... Medium and large also ... Behcet disease) Differential ... Syndrome #diagnosis #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Progression: • Upper lobe ... characteristic features Clinical ... and quantiferon-gold ... staining, NAA (PCR ... TB #Diagnosis #Management
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... : HSV 1): • Herpes ... virus • CMV • EBV ... • Common clinical ... /l is regarded as
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Excessive glutamate activity ... multiple spinal cord ... conditions listed in differential ... motor neurons - IV ... neurology #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Transverse Myelitis - Clinical ... simplex virus, HIV ... Myelitis #diagnosis #management ... #neurology #differential
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
Other +s: PCP, Histo ... positives: IVIG, IV ... >90% (In most clinical ... in BAL does not differentiate ... concurrent admin mold-active
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
noncompliance • Clinical ... initiation Clinical ... pleural effusions, CNS ... • Persistently active ... #Diagnosis #Management