11 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... , HIV, rubella legionella ... younger pts) Differential ... Disorders Such As ... hemolytic #anemia #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
/ AIDS - Differential ... should be based on clinical ... Inferomedial temporal lobes ... effect/Edema • EBV ... CNS #Infections #differential
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Progression: • Upper lobe ... characteristic features Clinical ... and quantiferon-gold ... staining, NAA (PCR ... TB #Diagnosis #Management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... to repair DNA, as ... Anticonvulsants - Gold ... Anemia #oncology #hematology ... #diagnosis #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Progression: • Upper lobe ... characteristic features Clinical ... and quantiferon-gold ... staining, NAA (PCR ... TB #Diagnosis #Management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Excessive glutamate activity ... multiple spinal cord ... conditions listed in differential ... motor neurons - IV ... neurology #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... matter, spinal cord ... Medium and large also ... Behcet disease) Differential ... Syndrome #diagnosis #management
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
infection (IFI) in hematologic ... cut-offs defined in clinical ... products - IV ... BAL GM does not differentiate ... concurrent admin of mold-active
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
Other +s: PCP, Histo ... positives: IVIG, IV ... >90% (In most clinical ... in BAL does not differentiate ... concurrent admin mold-active
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... • PET scan - activity ... scans and can also ... classification #hematology ... #oncology #management