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hematology agglutinin aids anemia behcet brain causes cold erythematosus gap globulin hemolytic hiv infections infectiousdiseases lesions lupus management monoclonal myopathy
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
Chorioretinitis • Diagnosis ... PCR 50% sensitive ... Lesions #Brain #differential ... #diagnosis #causes ... #radiology #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... Inferomedial temporal lobes ... Demyelinating disease ... effect/Edema • EBV ... #Infections #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome (CAS ... Viral infection, autoimmune ... - Mycoplasma, EBV ... CLL (older) • Autoimmune ... pts) Differential
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... basal ganglia, CNS ... CNS symptoms (headache ... ) Differential Diagnosis ... signs #symptoms #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... Scleromyxedema (CNS ... #Monoclonal #Differential ... #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... • Non-autoimmune ... rheumatologic diseases ... and CNS • Headache ... #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis Framework ... affects the skin, neurologic ... chorioretinitis, CNS ... #Diagnosis #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
• Heavy chain disease ... acute HIV, HBV, EBV ... Cirrhosis, ETOH, autoimmune ... Gap #ProteinGap #differential ... #diagnosis #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... RP-ILD), dermato-rheumatologic ... • ANA < 20 % IBM ... : • PBC, autoimmune ... #differential #
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