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differential management workup algorithm autoimmune cardiology endocarditis erythematosus fungal hematology igg4 infections lupus mycoses myopathy myositis phenotypes polycythemia related scleroderma
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... (interstitial lung ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... female, asian • Systemic ... biliary, renal, lung ... #phenotypes #workup ... #treatment #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... Infections • Malignancy ... Erythematosus #Diagnosis ... #Rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
frequently affected systems ... , this list is long ... can drive this disease ... As with many disease ... #Algorithm #workup
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Diagnosis ... Central nervous system ... and Arthritis Malignancy ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Non-Infectious (NTBE): • Malignancy ... , verrucous) - Lung ... Vascular: • Systemic ... underlying cause + Systemic ... #cardiology #infectiousdiseases
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... disease Malignancy ... dermatomyositis) Malignancy ... • Conduction system ... Myositis #Myopathy #rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... the circulatory system ... change in the lungs ... nails, bronchi, lungs ... ) #Mycoses #InfectiousDiseases
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