9 results
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)
Evaluation and Differential ... or alkalotic than ... Differential Diagnosis ... Disorders #Evaluation #workup ... #Differential #
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis ... alkalosis • Kidney ... #Metabolic #Alkalosis ... urine #Algorithm #nephrology ... #differential #
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Metabolic alkalosis ... Metabolic alkalosis ... D D-lactate (short ... Diagnosis #Summary #Nephrology ... #ABG #bloodgas
Normal Anion-Gap Acidosis (NAGMA) - Differential Diagnosis Framework and Workup

NAGMA
- Chem, ABG or VBG
- Calculate Anion
(NAGMA) - Differential ... NAGMA - Chem, ABG ... Chloride Intoxication ... #Metabolic #NAGMA ... #nephrology
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Hypokalemia Differential ... Algorithm Acidosis ... Metabolic alkalosis ... Diagnosis #Causes #Workup ... #Nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... Alkalosis: Differential ... chronic respiratory acidosis ... #Alkalosis #Differential ... Diagnosis #Causes #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
alkalosis • Normal ... (spot urine, calcium-creatinine ... ratio 0.5%) Differential ... Renal tubular acidosis ... Syndrome #diagnosis #nephrology
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
- Differential Diagnosis ... Beta-Agonists, ↑ work ... Inborn Errors of Metabolism ... • Presents as AG ... #Differential #
#ICUCard
RENAL
GFR
90-131
mL/min
((140-age)*Wt)/(72*Cr)
Glomerular Filtration Rate (Cockcroft)
CI Cr
90-131
mL/min
(CrU * volume)/CrS
Creatinine Clearance
FENa
0.0-1.0
%
((U/P Na)/(U/P Cr))*100
Fractional Excretion of Na+
Na req
mEq
(125-Na)*0.6*Wt
Required Sodium
FE Urea
(HCO3d-HCO3m) Metabolic ... Acidosis ІнСО3 ... Alkalosis ТНСО3 ... 9 Respiratory Acidosis ... -2min Calcium chloride