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rheumatology management druginduced sle activation arteritis cell classification comparison crisis cryoglobulinemia cryoglobulins dil disease erythematosus gca giantcell hemolytic laboratory macrophage
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory diagnosis ... , not a morphologic ... count, D-dimer, egg ... #Hematology #Pathology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... • Immunologic Workup ... Discontinuation of causal ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... the presence of anemia ... ANA and RF (if clinical ... #laboratory #workup
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... with leukopenia, anemia ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... Labs/Diagnosis: ... . systemic lupus
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... not be subtle e.g ... systemic complaints- anemia ... identifies 85 to 95% of cases ... them, but urgent rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... • Immunologic Workup ... Discontinuation of causal ... #diagnosis #treatment
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Crisis (SRC) Clinical ... microangiopathic hemolytic anemia ... rule out other pathology ... • Refractory cases ... Renal #Crisis #rheumatology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... red bone marrow, e.g ... • No CRAB - no anemia ... IFE, FLC assay Pathology ... #Workup #Hematology
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