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management oncology alopecia cvid erythematosus gap globulin hair hodgkins hypogammaglobulinemia immunodeficiency immunology loss lupus lymphoma mds myelodysplasia myelodysplastic naildisorders proteingap
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... to Systemic Diseases ... #Secondary #dermatology ... Diagnosis #Algorithm ... #causes
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
texture at bald spots ... weight loss • Chronic ... diet (caloric or protein ... #Diagnosis #dermatology ... #Hairloss
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... pancreatitis, protein-losing ... common • Antihistone ... with Lupus: • Chronic
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... gastric tumors • Hematology ... Comment on type ... #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... number of sites of disease ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... Most common cytopenia ... Marrow Failure • Chronic ... Myeloproliferative Disease ... #hematology #oncology
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