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differential blood management oncology product reactions agglutinin anemia cold common compared comparison disease distribution erythemas monoclonal paraproteinemias plasmacytoma primarycare rash
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... for anti-C3d and negative ... malignancies - B-cell ... sensitize red blood cells ... #anemia #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
potassium from lysed cells ... (rare), false negatives ... infographic by Nick ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
potassium from lysed cells ... (rare), false negatives ... in 650,000 by Nick ... #Transfusions #diagnosis ... #management #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Coombs (-) hemolytic ... Thrombosis in vascular beds-renal ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
fires, heating pads ... Well-circumscribed ... patches on the face, neck ... #differential #diagnosis ... #dermatology #compared
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
scale • Basal cell ... skin • Squamous cell ... Groin, axilla, neck ... ; pruritis #dermatology ... #differential #diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
in the head and neck ... EMP - head and neck ... Diagnosis? ... marrow biopsy negative ... #Workup #Hematology
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