7 results
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
after surgery/trauma ... • Underlying disease ... precipitates with calcium ... Acute CPP Crystal ... Gout #Comparison #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
after surgery/trauma ... Acute CPP Crystal ... onset of swelling, pain ... neck pain, fever ... #Rheumatology #
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
tubule of the kidney ... nephrocalcinosis • CPPD ... Malnutrition • Wilson's disease ... ALP -> PPi and Calcium ... respiratory failure • Neurologic
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Symptoms of Joint Disease ... Arthritis: • Acute ... Previous joint trauma ... #MSK #rheumatology ... approach #workup #differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Rhabdomyolysis: • Trauma ... nephrotoxicity to kidney ... of underlying disease ... potassium and calcium
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... crystals (gout) or calcium ... Screening Tests for Acute ... profile (e.g., calcium ... , and low back pain
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
affects the skin, neurologic ... musculoskeletal systems • Kidneys ... involvement, abdominal pain ... , Elevated AST ALT ... #Diagnosis #Rheumatology