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diagnosis differential anemia blood classification common cvid extravascular hemolytic hodgkins hypogammaglobulinemia immunodeficiency immunology intravascular leukostasis lymphoma lysis oncology product reactions
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... uremic syndrome ... Extravascular #Causes ... differential #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... iron deficiency, hemolysis ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... #hematology #secondary
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... Causes purpura & ... TRALI): Leading cause ... Transfusions #diagnosis #management ... #hematology #reactions
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and autoimmune hemolytic ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... antiinflammatory properties e.g ... #Rheumatology # ... diagnosis #management ... #Dermatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... nodosum • Immune hemolytic ... Hodgkin Lymphoma Workup ... classification #hematology ... #oncology #management
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