11 results
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
Types of hypersensitivity ... reactions Type ... Ill - Immune Complex-Mediated ... #reactions #Types ... #Classification
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Penicillin-induced drug reaction ... Antigen-Ab immune complexes ... Dermatitis (ie. reaction ... Allergy #Allergic #Reactions ... #Types #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
of hypersensitivity ... Allergen-specific lgE causes ... Antigen-antibody complex ... #reactions #types ... allergy #table #classification
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Hypersensitivity ... cell surfaces causes ... antigen-surface complex ... #Hypersensitivity ... #Types #Classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... Antigen-antibody complexes ... sclerosis #Hypersensitivity ... #Types #Classification ... Allergy #Diagnosis #Reactions
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... antibody-mediated immune reaction ... Antigen binds receptor ... (i.e. heparin) binds ... cell surfaces #Type2
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... to an allergic reaction ... Pre-formed lgE binds ... allergen-antibody complex ... Allergen-antibody complexes
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... • They can cause ... Cryoglobulins Cause ... vasculitis • Hypersensitivity ... #classification
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
depending on cell type ... Neutrophil bands ... Morphologically: absence of complete ... the underlying cause ... LEUKEMOIDREACTION #BANDS
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
disease, drug reactions ... occasional oligoclonal bands ... pauci-immune GN Immune Complex ... tract, and often causes ... inflammation Hypersensitivity