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diagnosis allergy hypersensitivity rheumatology definitions differential table comparison cryoglobulinemia cryoglobulins large medium pathophysiology reaction vasculitides vesselsize
Allergic Reaction Classification Type 1 reaction: Acute anaphylactic reaction Type 2 reaction: Cytotoxic reaction Type 3 reaction: Immune complex Type
Allergic Reaction ... Classification ... : Immune complex ... #Allergic #Reaction ... #Types #allergy
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Penicillin-induced drug reaction ... Antigen-Ab immune complexes ... Dermatitis (ie. reaction ... #Allergic #Reactions ... #Types #Classification
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
reaction • Type ... reaction • Type ... accumulation of small ... reaction • Type ... #Types #Classification
Types of hypersensitivity reactions Type I - lgE-Mediated, Within I Hour (Anaphylaxis) Type II - IgG or IgM
reactions Type ... Ill - Immune Complex-Mediated ... hypersensitivity #reactions ... #Types #Classification ... #Allergy #Diagnosis
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
hypersensitivity reactions ... Antigen-antibody complex ... Antigen-antibody complexes ... #types #allergy ... #table #classification
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
When the specific allergen ... , and drug allergies ... Antigen-antibody complexes ... #Classification ... #Diagnosis #Reactions
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
Small vessel vasculitis ... although immune complex ... small vessel vasculitis ... can affect any type ... Medium #Large #Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... Types: • Type ... • Cutaneous small-vessel ... vasculitis • ... #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
abnormalities SMALL ... tracts Immune Complex ... disease, drug reactions ... pain, infarct • Small ... #rheumatology #classification
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