10 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
peanuts), Hay fever ... Immunological Mediator: IgM ... Antigen-Ab immune complexes ... Contact Dermatitis (ie ... #Types #Classification
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... complex -> Allergen-antibody ... complexes bind ... peanuts) • Hay fever ... #Immunology #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... , seasonal hay fever ... Antigen-antibody complexes ... Hypersensitivity #Types #Classification ... #Pathophysiology
Algorithm for the differentiation between simple and complex febrile seizures. Guidelines for evaluation of each. #Diagnosis
Algorithm for the ... between simple and complex ... Diagnosis #Management #EM ... FebrileSeizure #Fever ... #Seizure #Algorithm
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
schema of the pathophysiology ... metabolism, excluding complex ... connections and pathophysiology ... #Diagnosis #Algorithm ... Pediatrics #Table #IEM
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
Type II - IgG or IgM ... Type Ill - Immune Complex-Mediated ... reactions #Types #Classification ... #Allergy #Diagnosis
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
of lab values compiled ... See IEM schema for ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... NICU #Genetics #IEM
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Anaphylaxis, Hay fever ... Mediators: IgG/ IgM ... Antigen-antibody complex ... Antigen-antibody complexes ... #table #classification
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
antigen-surface complex ... antigen-surface complex ... antibodies (IgG, rarely IgM ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Serious Bacterial Illness (SBI):
1) UTI and pyelonephritis
Most common cause of SBI
Accounts for 3-8% of uncharacterized fevers
Female
uncharacterized fevers ... (particularly complex ... Diagnosis #Peds #EM ... #Classification ... #Fever #SBI #SeriousBacterialIllness