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diagnosis adrenal insufficiency differential causes pathophysiology signs symptoms workup addisons ai breast calcium cosyntropin cushings discharge disease evaluation homeostasis hypercortisolism
Adrenal Insufficiency Differential Diagnosis Algorithm Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis Algorithm ... ) stimulation test ... - Primary adrenal ... Differential #Diagnosis #Algorithm ... #endocrinology
Diagnosis Adrenal Insufficiency - Algorithm Step 1) Screening Test: 6-8AM Cortisol Level - Early morning cortisol levels
Insufficiency - Algorithm ... Differentiate primary ... consistent with primary ... Insufficiency #Algorithm ... #Stimulation #Endocrinology
Adrenal Insufficiency Diagnosis Algorithm Clinical features: - Weight loss, anorexia, Weakness, fatigue, GI distress - Hypotension,
Insufficiency Diagnosis Algorithm ... skin (due to high ACTH ... stimulating melanocytes ... , only seen in PRIMARY ... #StimTest #Endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
Insufficiency Diagnosis Algorithm ... Axis Response to ACTH ... Insufficiency #Diagnosis #Algorithm ... #ACTH #Stimulation ... #Test #Endocrinology
Primary vs Secondary Adrenal Insufficiency - Pathophysiology Primary AI = adrenal glands themselves are the problem. This
Primary vs Secondary ... be low, while ACTH ... Low ACTH leads to ... limited adrenal stimulation ... Pathophysiology #endocrinology
Primary Adrenal Insufficiency: • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Primary Adrenal ... stimulation test ... autoimmune-mediated primary ... stimulation test ... diagnosis #testing #endocrinology
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm Primary Adrenal Insufficiency: • Autoimmune primary adrenal insufficiency • Adrenoleukodystrophy,
Diagnosis Workup Algorithm ... Primary Adrenal ... • Autoimmune primary ... apoplexy • Isolated ACTH-deficiency ... #endocrinology
Adrenal Insufficiency Diagnosis Algorithm Test 1: Baseline AM Cortisol - Beware of major normal value -
Insufficiency Diagnosis Algorithm ... pregnancy) Test 2: ACTH ... Stimulation - ... Insufficiency #Diagnosis #Algorithm ... #endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm ACTH-Dependent (Secondary): • Pituitary Dysfunction • Hypothalamic Dysfunction ACTH-Independent (Primary):
Differential Diagnosis Algorithm ... ACTH-Dependent ... Hypothalamic Dysfunction ACTH-Independent ... (Primary): • Autoimmune ... #Causes #endocrinology
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Primary Adrenal ... AM cortisol and ACTH ... AI present - ACTH ... stimulation test ... addisons #disease #endocrinology
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