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algorithm anemia hemolysis rheumatology cell classification cryofibrinogenemia extravascular hodgkins intravascular lymphoma management mds myelodysplasia myelodysplastic nonpalpable palpable petechiae petechial physicalexam
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... usually IgM) (e.g. primary ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... (CVID, WAS), (neurologic ... hematologic disorder ... Diagnosis #Causes ... #Workup #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
iron deficiency, hemolysis ... Chronic inflammatory disorders ... Post-splenectomy Primary ... #Diagnosis #Causes ... #hematology #secondary
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... /Quantity: • Primary ... DIC/TTP/HUS - Hemolytic ... #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Abnormalities in primary ... Vasculitis - Collagen disorders ... deficiency Work ... #Causes #dermatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... • Anemia • Pruritis ... Hodgkin Lymphoma Workup ... classification #hematology ... #oncology #management
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Primary (essential ... • Painful or pruritic ... cryoglobulins • Negative causes ... Biopsy: Typical pathologic ... hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Biopsy: Solitary disorder ... except for the primary ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology
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