6 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Syndrome: • Clinical ... - GPA, EGPA, microscopic ... polyangiitis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
(GPA) Skin involvement ... GPA causes disease ... Rarely dominate the clinical ... reticularis Differential ... #GPA #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
PR3-ANCA): • Microscopic ... Polyangiitis: ... tract, and often causes ... and branches • GCA ... Serologies for Cryoglobulins
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... , EGPA, Microscopic ... immunoglobulins & cryoglobulins ... • Skin biopsy
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Elevated ESR and CRP GCA ... develop in pts with GCA ... (PR3-ANCA)): Microscopic ... tract, and often causes
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... very remarkable w/differential ... in literature (NEJM ... required due to skip ... (Cornelia NEJM