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diagnosis rheumatology alopecia anemia cll cryofibrinogenemia dermatology gravis hair hairloss infections leukemia loss lymphocytic mds myasthenia mycobacteria myelodysplasia myelodysplastic myopathy
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Anemia Clinical ... Constitutional Syndromes ... marrow-failure syndromes ... myelodysplastic syndrome
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... #hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
disorder of the ... thyroid, Sjogren syndrome ... “dropping head syndrome ... - Kearns-Sayre syndrome ... Eaton myasthenia syndrome
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Alopecia mucinosa, Aplasia ... , Loose anagen syndrome ... Examination: • Signs ... weight loss • Chronic ... Dermatitis (Consider HIV
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... just beneath the skin ... • Anemia • Aplastic ... Marrow Failure • Chronic ... #oncology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... associated with autoimmune ... cryoglobulins • Negative causes ... Biopsy: Typical pathologic ... Antiphospholipid syndrome
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Lady Windermere Syndrome ... : • Syndrome of ... Hematologic malignancy ... NTM #Infections #differential
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... Antisynthetase syndrome ... lymphoma Overlap Syndrome ... ANTI-SYNTHETASE SYNDROME ... paraneoplastic syndrome
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