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hematology workup causes hemolytic aggregometry algorithm classification comparison defects extravascular hodgkins inherited intravascular lymphoma management mds myelodysplasia myelodysplastic nonpalpable palpable
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... Gplb receptor • Thrombcytopenia ... #disorders #hematology ... #hemepath #differential ... #diagnosis #Aggregometry
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... MYH9-Related Disorder ... Defects #comparison #table ... #differential # ... diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... with or without platelet ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder ... #Anemia #Differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #Diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... - Differential ... Diagnosis and Workup ... changes), high MCV anemia ... #Platelet #Disorders
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Platelet count ... anemia Indirect ... WBC count and differential ... #Workup #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... count (thrombocytopenia ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... nodosum • Immune hemolytic ... - Low Hb and platelets ... Immunohistochemical studies (to differentiate ... #oncology #management
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